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KMID : 0380020200350030235
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Korean Journal of Biotechnology and Bioengineering
2020 Volume.35 No. 3 p.235 ~ p.243
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Cosmetic Composition for Skin Improvement Containing Aloe vera Adventitious Root Extract
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Kim Dong-Myong
Jung Ju-Yeong
Lee Hyung-Kon
Kwon Yong-Seong
Baek Jin-Hong
Han In-Suk
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Abstract
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The objective of this study was to investigate whether extracts of aloe vera adventitious root produced by plant tissue culture technology has better effects on anti-wrinkle effect and skin-brightening than aloe vera extracts by performing in vitro assays. Aloe vera adventitious root and aloe vera were extracted by either water or 70% ethanol. Among water extract of aloe vera, water extract of aloe vera adventitious root, ethanol extract of aloe vera (AVE) and ethanol extract aloe vera adventitious root (AVRE), nitric oxide production inhibitory activity was the highest at AVRE, with a value of 62.28%. Inhibitory activities of matrix metalloproteinase (MMP)-1 and MMP-3 syntheses were highest at AVRE (65.11 and 37.21%, respectively). When analyzing synthetic activity of type I procollagen which has an anti-wrinkle effect, AVRE showed higher value by 379.43% than UV-irradiated control group. The anti-melanogenic activity which correlates skin-brightening effect was also the highest at AVRE (83.77%), although, inhibitory activity of tyrosinase was not shown. Moreover, the value of DPPH radical scavenging activity of AVRE was higher than that of AVE by more than 10 times. From these results, it was confirmed that aloe vera adventitious root has better effect on wrinkle prevention and skin-brightening than aloe vera.
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KEYWORD
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aloe vera, adventitious root, tissue culture technology, antioxidant, anti-wrinkle, skin-brightening
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